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Tom G Schwan Selected Research

Relapsing Fever

1/2020Transgenic functional complementation with a transmission -associated protein restores spirochete infectivity by tick bite.
10/2015Vaccination with the variable tick protein of the relapsing fever spirochete Borrelia hermsii protects mice from infection by tick-bite.
1/2013Periplasmic flagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii.
1/2012Endemic foci of the tick-borne relapsing fever spirochete Borrelia crocidurae in Mali, West Africa, and the potential for human infection.
4/2010A novel surface antigen of relapsing fever spirochetes can discriminate between relapsing fever and Lyme borreliosis.
12/2009Characterization of a novel relapsing fever spirochete in the midgut, coxal fluid, and salivary glands of the bat tick Carios kelleyi.
8/2009Identification of conserved antigens for early serodiagnosis of relapsing fever Borrelia.
12/2008Relapsing fever spirochetes retain infectivity after prolonged in vitro cultivation.
11/2008Oms38 is the first identified pore-forming protein in the outer membrane of relapsing fever spirochetes.
8/2007Purine salvage pathways among Borrelia species.
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Tom G Schwan Research Topics

Disease

17Relapsing Fever
01/2020 - 02/2003
11Infections
01/2019 - 02/2002
7Lyme Disease (Disease, Lyme)
04/2010 - 02/2003
3Persistent Infection
04/2014 - 10/2005
2Tick Bites
01/2020 - 10/2015
1Tick-Borne Diseases (Tick-Borne Disease)
08/2009
1Fever (Fevers)
01/2007
1Thrombocytopenia (Thrombopenia)
10/2003
1Coinfection
10/2002

Drug/Important Bio-Agent (IBA)

11Proteins (Proteins, Gene)FDA Link
01/2020 - 03/2004
4AntibodiesIBA
01/2012 - 12/2006
4AntigensIBA
04/2010 - 06/2006
3Membrane Proteins (Integral Membrane Proteins)IBA
01/2020 - 03/2004
3Immunoglobulin M (IgM)IBA
04/2010 - 12/2006
3glycerophosphodiester phosphodiesteraseIBA
08/2009 - 02/2003
3DNA (Deoxyribonucleic Acid)IBA
12/2008 - 10/2005
21-oleoyl-2-stearoylphosphatidylcholineIBA
01/2020 - 10/2005
2VaccinesIBA
01/2017 - 10/2015
2Lipoproteins (Lipoprotein)IBA
12/2006 - 02/2002
2EnzymesIBA
05/2006 - 02/2003
2OspC proteinIBA
10/2005 - 03/2004
1Protein Sorting Signals (Signal Peptide)IBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2019
1Therapeutic UsesIBA
01/2017
1Recombinant ProteinsIBA
04/2010
1Surface Antigens (Surface Antigen)IBA
04/2010
1IntegrinsIBA
01/2010
1LigandsIBA
01/2010
1Concatenated DNAIBA
12/2009
1Immunoglobulin G (IgG)IBA
08/2009
1PorinsIBA
11/2008
1OspA proteinIBA
11/2008
1Amino AcidsFDA Link
11/2008
1HypoxanthineIBA
08/2007
1purineIBA
08/2007
1benzophenone-4'-heptyl-4-pentanoic acidIBA
05/2006
1Serine Proteases (Serine Protease)IBA
05/2006
1NicotinamidaseIBA
07/2005
1Platelet Glycoprotein GPIIb-IIIa ComplexIBA
10/2003
1Phospholipids (Phosphatides)FDA LinkGeneric
02/2003
1Anti-Bacterial Agents (Antibiotics)IBA
10/2002
1Biological ProductsIBA
02/2002